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After 14 days, a significant increase in energy expenditure at rest of 6% was observed

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This response difference is consistent with previous reports in zebrafish identifying initial BPA-induced hyperactivity in response to acute/early exposure 34,35 but later reductions in locomotor behavior 35

These work well for people following plant-based diets or who cannot tolerate large amounts of animal products

The concept of systemic protection originating from the gut makes evolutionary sense