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Longitudinal monitoring of these biomarkers may help identify individuals with persistent redox imbalance and stratify risk by exposure duration and chronotype

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[48] [49] [50] [51] [52] [53] [54] Dihydrolipoic acid (DHLA) can also form intracellularly and extracellularly via non-enzymatic, thiol-disulfide exchange reactions

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It is suggested that the differential modulation of MR co-factors is associated with the specific ability of finerenone to improve the expression of tenascin X (TNX), an MR target gene that plays a crucial role in fibrosis regulation (211)