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Safety specification

The ASIR and ASMR for males were substantially higher than those for females, highlighting a persistent gender disparity in the burden of the disease

There was also one crucial additive

Vaccines (Basel) 11 , 1862 (2023)

Nicotine can increase blood pressure, Safety and Side Effects: Stomach ulcer or diabetes, Safety and Side Effects: A history of seizures Safety and Side Effects: Ask a doctor or pharmacist before use if you are: Safety and Side Effects: Using a non-nicotine stop smoking drug, Safety and Side Effects: Taking prescription medicine for depression or asthma