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An interesting facet of our data is the lack of a relationship between the nicotine contents of the NPs and the pharmacokinetic parameters C max and AUC, while the existence of such a relationship has been demonstrated for other oral nicotine products such as nicotine gum [30]

Cotinine is then circulated in the blood and can be found in various body fluids and tissues, including urine, blood, saliva, hair, and even breast milk

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