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Senescence refers to cells that enter into a distinct state characterized by dysfunctional mitochondria, increased production of ROS, and an altered secretory profile as a consequence of DNA damage, telomere shortening and an altered environment (Sikora et al., 2021)

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Individual Risk Factors and Genetic Considerations Genetic variants in GLP-1 receptor (GLP1R) and glucose-dependent insulinotropic polypeptide receptor (GIPR) pathways may influence individual susceptibility to gastrointestinal side effects

prognosis (n=48)

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