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Genes such as SCN1A, SCN2A, and SCN1B encode voltage-gated sodium channels, while GABRA1, GABRB3, GABRG2 which encode subunits of the GABA-A receptor to mediate inhibitory neurotransmission can increase the risk of seizures and linked to various forms of epilepsy

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J Neurochem 48 : 601608