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Highlighting the challenges of the online realm, Altria's June 2024 halt of ZYN.com sales came in the wake of a District of Columbia subpoena, underscoring the heightened legal and reputational stakes tied to online channels and their scrutiny over youth access

Two systematic reviews examining data from Europe and North America found that young people who experiment with alternative nicotine delivery systems are roughly three to four times more likely to later begin smoking conventional cigarettes than non-users

doi: 10.1186/S12889-025-22107-6 10

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