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The biological environment in which they work dramatically affects their effectiveness

Gan Y, Meng D, Lang L, Luo J, Dai P, Chang C, et al

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ROS, particularly hydroxyl radicals, interact with DNA bases, leading to base modifications, strand breaks, and the formation of oxidative lesions

In our previous study, the decrease in eGFR was slower in patients treated with SGLT2i than in those treated with GLP1Ra during monotherapy ( Another possible mechanism may be the difference in the mean BP at the time of drug treatment

Supplements : Consult with your healthcare provider about any supplements you are taking to ensure they do not interfere with the therapy