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Another concern comes from the use of hyaluronic acid injections, which can cause postoperative complications that might affect patient satisfaction

Diabetes Care 45(11):27532786

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Therapies that rely on scaffold-free cellular approaches, such as ACI, are not designed to handle these mechanical burdens early post-surgery, and thus, utilizing scaffolds with improved bulk mechanical properties could increase efficacy of treatment and promote earlier return to normal activity in these knees

10.1152/ajpcell.00272.2006 Am