CGRP was decreased by 6275% in rats with capsaicin treatment, while TH was not different between the rats with and without capsaicin treatment
This modulation may lead to better-supported subperiosteal bone formation, resulting in a potential increase in bone dimensions without necessarily altering the intrinsic volumetric mineral density
Summary: Mounjaro (tirzepatide) is not contraindicated in Graves' disease, but thyroid function must be stable and well-controlled before initiation, with ongoing monitoring of both thyroid and glycaemic parameters
It's still a side effect today, right
Novakova K, Kummer O, Bouitbir J, Stoffel SD, Hoerler-Koerner U, Bodmer M, Roberts P, Urwyler A, Ehrsam R, Krhenbhl S
This maintains maximum stability and prevents the peptides from degrading over extended periods