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Safety of exenatide once weekly in patients with type 2 diabetes mellitus treated with a thiazolidinedione alone or in combination with metformin for 2 years

It is associated with improving body composition by supporting fat reduction while maintaining lean muscle mass

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More severe side effects are possible but less common

The means of different groups were compared using the Student (t) test

REDEFINE-4 reported about 25.5% at 84 weeks in a head-to-head trial