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We propose that the levels of certain hormones in tobacco leaves and roots undergo changes following topping, as compared with their pre-topping levels

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Nicotine itself impairs sperm quality regardless of delivery method by affecting the HPG axis and reducing testosterone production

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Ever- daily smoking Hispanic and African American students had a Table 1 Odds ratios and 95% confidence intervals (OR, 95% CI) for receipt of citation, vicarious citation, threat of driving licence suspension, sociodemographic, smoking, and smoking related influences predicting intentions to smoke next year for non-smokers, experimental smokers, and ever-daily smokers (n = 28249) Variable Non-smokers Experimental smokers Ever-daily smokers OR (95% CI) OR (95% CI) OR (95% CI) (n = 14473) (n = 7929) (n = 5847) School level effects Percentage current smokers 1.00 (0.98 to 1.01) 0.99 (0.97 to 1.01) 1.00 (0.98 to 1.02) *School prevention programme 1.01 (0.75 to 1.36) 1.15 (0.98 to 1.34) 0.97 (0.80 to 1.18) Individual level effects Sex 1.05 (0.83 to 1.33) 0.74 (0.63 to 0.87) 0.77 (0.63 to 0.94) Age (years) 0.92 (0.85 to 0.99) 0.84 (0.80 to 0.89) 1.03 (0.95 to 1.11) `African American 0.90 (0.64 to 1.29) 1.12 (0.90 to 1.38) 0.44 (0.34 to 0.59) 1Hispanic 1.65 (1.25 to 2.16) 1.75 (1.47 to 2.09) 0.75 (0.60 to 0.93) Amount smoked 1.43 (1.38 to 1.49) 1.45 (1.37 to 1.54) Household smoking 1.30 (1.03 to 1.64) 0.98 (0.84 to 1.15) 1.17 (0.96 to 1.43) Number of friends who smoke 1.52 (1.41 to 1.65) 1.32 (1.25 to 1.40) 1.31 (1.24 to 1.39) Tolerance for smoking related deviance 1.39 (1.33 to 1.45) 1.27 (1.22 to 1.32) 1.14 (1.10 to 1.18) Threat of licence suspension 1.11 (0.77 to 1.62) 1.00 (0.82 to 1.22) 0.70 (0.57 to 0.88) Vicarious MIP citation 2.13 (1.69 to 2.17) 1.01 (0.86 to 1.18) 1.12 (0.92 to 1.36) MIP citation 1.07 (0.70 to 1.65) 0.70 (0.47 to 1.07) Tolerance 6 threat of licence suspension 1.15 (1.04 to 1.27) NA NA Tolerance 6 vicarious MIP citation 1.17 (1.09 to 1.27) 0.92 (0.87 to 0.98) NA NA, confidence interval included the value of 1.0 and therefore was not interpreted