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They are electrically powered devices enabling the release of airborne nicotine without any combustion process

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[65] [66] In the few cases in which lung biopsies were performed, the results were consistent with acute lung injury and included a broad range of features, such as acute fibrinous pneumonitis, diffuse alveolar damage, lipid-laden macrophages, and organizing pneumonia

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Cigarette smoking has been linked to the development of many autoimmune disease, including rheumatoid arthritis, systemic lupus erythematosus, multiple sclerosis, Graves disease, and primary biliary cirrhosis 23,24,25