Mechanistic and Translational Research Further investigation into the molecular mechanisms of action could help optimize clinical applications and identify novel therapeutic targets
doi: 10.1007/S13577-024-01038-1/FIGURES/8 85 KapoorISarvepalliSMDAlessioDGrewalDSHadziahmetovicM
Generative AI statement The author(s) declared that generative AI was used in the creation of this manuscript
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ClinicalTrials.gov lists early human research, including a Phase I safety and pharmacokinetic study and a more recent Phase II study involving acute hamstring injury
Moreover, presenting that the most threatening period may be the seizures-period, and the regular duration estimated to be 5 hours, and that at the time point of 3 hours following paracetamol the rats would exhibit generalized convulsions for the next two subsequent hours, it is interesting that after BPC 157 application the generalized convulsions disappeared within the next 25 minutes and the rats regained posture, still sleepy, with a tottering walk for the next 50 minutes
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