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Acetaldehyde in mainstream tobacco smoke: Formation and occurrence in smoke and bioavailability in the smoker

The different ingredients used in paan and gutkha have their own detrimental effects, such as catechu, which consists of tannin and polyphenols, which have a high tendency to cause esophageal cancer and are characterized by mutagenicity and clastogenicity [52-54]

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Additionally, the condition may lead to loose teeth and eventually, tooth loss