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Thus, understanding the consequences of crosstalk between nicotine/nAChRs and sirtuin signaling pathways in the regulation of drug resistance could be a critical implication for cancer therapy

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Available at: [Accessed 23 August 2018] [72] Elkin L, Thomson G, Wilson N

When people were followed for 20 years, researchers found that an occasional joint didnt appear to have any discernable effect on long-term lung function, though there may be some accelerated decline in pulmonary function among those smoking joints every day for decades, so marijuana moderation is suggested

A SUMOylation-dependent pathway regulates SIRT1 transcription and lung cancer metastasis