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In the cohort study, the researchers used 2013 to 2021 nationwide registry data from Sweden and Denmark to assess suicidality, self-harm or depression among new users of either GLP-1 receptor agonists or sodium glucose cotransporter-2 (SGLT2) inhibitors

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Concomitant glucose-lowering medications were also different between the groups before matching, with a lower proportion of individuals on oral medications and more on insulin in the SGLT2i group

Ciliary neurotrophic factor in patients with primary open-angle glaucoma and age-related cataract

These aspects are deeply interconnected with the underlying mechanisms of migraine pathophysiology as depicted in Figure 1