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Mice without the CHRNA2 gene showed no differences from the control group when researchers fed them a regular diet

There are different restrictions on advertising tobacco products and the health warnings that come with the advertising and need to be on packets (USA, Europe)

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Alcohol Research: Current Reviews, 40 (1)

Combustible and smokeless tobacco use among high school athletes United States, 20012013

For smokers trying to quit, Marousek recommends the use of other nicotine sources such as gum, lozenges or a nicotine patch