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As we age, collagen production naturally declines, leading to the formation of wrinkles, fine lines, and sagging skin

Tarangelo et al, 2018

But based on the testing that we did, we said like you should, you should probably experiment with 700, 800 milligrams

In senescent cells, FOXO4 binds to p53 and prevents apoptosis, allowing these damaged cells to persist

However, nearly all data come from lab and animal studies rather than controlled human trials, so claims about systemic hormone changes warrant caution

Not always, but labs can help when symptoms point to anemia, thyroid shifts, low vitamin D, or hormone shifts