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Smoking is the major risk factor for COPD, and cigarette smoke (CS)-induced oxidative stress can lead to the damage of airway epithelium and compromise the barrier function, which is the initial step and pathological basis of COPD progression [3,4,5,6]

This article is part of the Topical Collection on Allergies and the Environment Rights and permissions About this article Cite this article Hickman, E., Jaspers, I

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