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The medical evaluation includes: Review of your health history, including current medications, medical conditions, allergies, and previous weight loss attempts Assessment of your eligibility for GLP-1 therapy based on BMI, health conditions, and contraindications Discussion of treatment options, expected outcomes, potential side effects, and risks Determination of the appropriate medication (semaglutide or tirzepatide), starting dose, and titration schedule A prescription written by a licensed healthcare provider (physician, nurse practitioner, or physician assistant) who has determined that GLP-1 therapy is medically appropriate for you This evaluation can occur in-person with your primary care provider or specialist, or via a telehealth platform like FormBlends

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There were two major randomized trials in which metformin vs

REWIND (2019) Dulaglutide extended benefit into a broader, lower-risk population challenging the idea this was only for those with established disease