The brain becomes more sensitive to hunger cues
Limited research shows no dose adjustments needed
In certain embodiments, any controlled-release otic formulation described herein increases the exposure of an active agent and increases the Area Under the Curve (AUC) in otic fluids (e.g., endolymph and/or perilymph) by about 30%, about 40%, about 50%, about 60%, about 70%, about 80%, about 90%, about 100%, or higher than 100%, compared to an otic formulation that is not a controlled-release otic formulation
Easy injection & fast results
Formal inclusion means the FDA has determined, after applying its statutory and regulatory process, that a specified bulk drug substance can be used under the section 503A bulks-list pathway when all other conditions are met
Now layer MOTS-C on top