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J.KimH.-M.et al (2006)

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Many of these benefits relate to weight loss, but studies are underway to understand how these medications might affect health through additional mechanisms

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Endothelial GLP-1 (glucagon-like peptide-1) receptor mediates cardiovascular protection by liraglutide in mice with experimental arterial hypertension

Others prefer intermittent approaches: taking medication for 6-12 months, stopping to assess their natural baseline, and restarting if weight regain occurs