The placebo group lost an average of 2.4%
In the STEP 1 trial, adults with overweight or obesity without diabetes who took semaglutide 2.4 mg lost an average of 14.9% of their body weight at 68 weeks
Before prescribing, I also make sure you have no contraindications to the particular medication prescribed, such as a history of pancreatitis, a personal or family history of a rare form of thyroid cancer called medullary thyroid cancer, or multiple endocrine neoplasia type 2
They reflect real clinical practice where patients know their treatment and can make informed decisions about continuing therapy
Tirzepatide, sold under the brand name Mounjaro, is a dual-action medication that targets both GLP-1 and GIP (glucose-dependent insulinotropic polypeptide) receptors
The highest tirzepatide dose group achieved an average weight loss of more than 20% in that trial