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Smoking caused accumulation of cadmium in the body, which induced the apoptosis of AF cells and in turn caused IVD degeneration (Jing et al., 2020)

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For most smokers, the early days involve a tremendous amount of effort

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Six different treatments were established based on daily cigarette smoke concentration (CSC/Day): 0 (control), 2, 4, 6, 8, and 10 cigarettes per day, respectively

Additionally, smoking plays a role in the development of various liver diseases such as cirrhosis and hepatitis