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To investigate this putative lineage relationship, we targeted the POU2F3 and FOXI1 TF genes, required for tuft cell 19 and ionocyte specification, respectively 17,19 , using CRISPR/Cas9 KO in human tracheal basal cells ( n = 5 donors, Supplementary Fig

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Women who smoke during their pregnancy are at increased risk of: complications during labour, miscarriage, premature and still births, low birth weight and sudden infant death syndrome (SIDS)