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In addition, the fourth line of defense may be activated by the reaction and generation of free radicals, which in turn induces the production and transport of corresponding antioxidant enzymes to the effective site and causes the formation of catalase and superoxide dismutase [32, 35]

The index of bioavailability (F) was calculated using the AUC data obtained in an intravenous pharmacokinetics study with the same test article (RBM Exp

Life Sci 28:16551663