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D2 receptors in the mesolimbic pathway may become overactive, contributing to psychotic symptoms like hallucinations

JACC Basic Transl Sci 7(1):8498 Cheng X, Zhao H, Wen X, Li G, Guo S, Zhang D (2023) NLRP3-inflammasome inhibition by MCC950 attenuates cardiac and pulmonary artery remodelling in heart failure with preserved ejection fraction

More options are good news for patients, and the expansion of this drug class will make it easier for individuals to optimize their type 2 diabetes management

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It is FDA-approved for Type 2 diabetes but is sometimes prescribed off-label for weight loss