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Oxidative stress leads to imbalances in seminal plasma antioxidants, which is the main mechanism of a high semen viscosity, resulting in sperm DNA damage, sperm chromatin instability, membrane lipid peroxidation, and a low fertilization rate (Figure 1) (58)

Specifically, the long-term health and economic benefits of preventing chronic conditions must be factored into coverage decisions while also balancing the budget impact

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doi: 10.1157/13054318 91 QuJLiYZhongWGaoPHuC

Research reported in JAMA in December 2023 also emphasized that patients may need to stay on the medications long term in order to keep the weight off