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Deletion of leucine 61 in glucose-6-phosphate dehydrogenase leads to chronic nonspherocytic anemia, granulocyte dysfunction, and increased susceptibility to infections

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Side effects are rare but can include nausea, vomiting, increased agitation, weight loss, and restlessness

(2019) "MOTS-c nuclear translocation under metabolic stress." Published in Cell Metabolism

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It slows stomach emptying, which extends satiety, and it improves blood sugar stability to reduce cravings