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Contact your GP or diabetes specialist nurse if: Body aches are severe, persistent, or progressively worsening despite self-care measures You develop muscle weakness that interferes with daily activities or mobility Aches are accompanied by dark-coloured urine, which could indicate rhabdomyolysis (a rare but serious condition involving muscle breakdown) [11] [12] You experience symptoms of dehydration that do not improve with increased fluid intake, such as dizziness, reduced urine output, or confusion Body aches are associated with signs of infection, including fever, chills, or localised redness and swelling Seek urgent medical attention (call 999 or attend A&E) if: You develop severe muscle pain with significant weakness, particularly if accompanied by dark urine You experience chest pain, severe abdominal pain, or difficulty breathing alongside body aches You have symptoms suggesting severe hypoglycaemia (confusion, loss of consciousness, seizures) You develop signs of pancreatitis, such as severe, persistent abdominal pain radiating to the back, with or without vomiting Call NHS 111 if you are unsure about the urgency of your symptoms or need advice outside of normal GP hours

The most common (water retention, tingling, injection site reactions) resolve on their own or with dose adjustments
Vitamin B12 is essential for keeping circadian rhythms in sync
That said, creatine monohydrate has a robust evidence base for supporting muscle mass and strength in adults, including older adults, and is generally considered safe
since publication of the SELECT trial results, semaglutide is now approved for use by the US Food and Drug Administration (FDA) to reduce the risk of MACE in adults with established CVD and obesity or overweight [22], in addition to regulatory approval by the European Medicines Agency (EMA) and other major markets