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Smokers were also 3.3 times more likely to develop wound infections and three times more likely to develop necrosis
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This modification involves the addition of methyl groups (-CH3) to cytosine residues, typically at CpG dinucleotide sites, and is catalyzed by a family of enzymes known as DNA methyltransferases (DNMTs) (35,36)
Founder Burton Rubin allegedly got the idea to create his double-wide papers in 1969 after watching some of his law school classmates connect two regular-sized papers to roll a larger joint
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