SA--Gal staining showed that rapamycin decreased senescence, whereas 3-MA promoted senescence (Fig
2.2 Defective energy metabolism and increased oxidative stress in mitochondria To execute energy production and substance metabolism are the main functions of mitochondria (Spinelli and Haigis, 2018
Together with glutathione, they provide dual protection against free radicals, supporting skin health, immunity, and anti-ageing at the cellular level
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