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**Based on the totality of evidence available for IQOS in comparison with continuing to smoke

More women are affected than men Technological innovations in vaping Since the beginning, the vaping industry has had regular innovations that allow manufacturers to launch or develop new products

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Between 2020 and 2025, Colorado's average pack price climbed from $6.06 to $10.85, a 79% increase and a jump of 19 ranking spots, the largest of any state

The proliferation othe f illicit cigarette trade poses a significant challenge to the cigarette market