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Rose S, Bennuri SC, Murray KF, Buie T, Winter H, Frye RE (2017) Mitochondrial dysfunction in the gastrointestinal mucosa of children with autism: a blinded case-control study

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Metabolic reprogramming driven by oncogenes allows cancer cells to maintain deregulated cell proliferation, withstand metabolic challenges that are associated with diminished oxygen and nutrients, maintain a dedifferentiated state through alterations in global patterns of gene expression, and corrupt the surrounding microenvironment to actively facilitate tumor growth and dissemination 16,17,18

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