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At first glance, the move looked like diversification

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All studies met 60% of the criteria, with 85.60% being the mean percentage of criteria met

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Alkaloid levels are highest in the unripe fruits, so they provide a stronger stimulating effect

This provides a molecular framework for understanding how local epithelial injury escalates to systemic organ dysfunction, but they do not yet establish epithelial mitophagy imbalance as the sole or direct upstream driver of all forms of bidirectional kidneylung crosstalk