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Journal of Experimental Biology 2004

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However, if extremely high doses are given for a long time, pyridoxine can cause nerve damage leading to numbness or tingling in the hands and feet (peripheral neuropathy)

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Zepbound (tirzepatide): Similar to the relationship between Ozempic and Wegovy, Zepbound contains the same active ingredient as Mounjaro but is FDA-approved for chronic weight management in adults with obesity (BMI 30) or those who are overweight (BMI 27) with at least one weight-related condition