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"But the challenge is how do you make them accessible to those kind of people and encourage use, without also making people use them who otherwise would not use nicotine." It's unknown how federal regulators will rule

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None of the retailers in the sample sold combustible cigarettes

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However, these changes were not observed after 4 weeks of exposure and only observed in mice exposed to e-cig aerosols of PG/VG with nicotine and tobacco flavor 36