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The clinical data shows that weight loss occurs with semaglutide alone, but combining the medication with physical activity improves body composition, preserves muscle mass, and produces better long-term outcomes

Presented at the American Heart Associations 2023 Scientific Sessions (1113 November, Philadelphia, USA), the results of the SELECT trial showed that overweight or obese people without diabetes taking semaglutide for more than three years had a 20% lower risk of heart attack, stroke or death due to cardiovascular disease and lost an average of 9.4% of their body weight

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In the pancreas, they support insulin sensitivity and balanced glucose response

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