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Because it works through the same GHRH receptor and relies on somatostatin feedback for regulation, it is essentially incapable of driving runaway GH secretion regardless of dose, as shown in data reviewed by Bedimo et al

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doi:10.1056/nejmoa2203364 106 Ng JWG, Cairns SA, OBoyle CP

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Thats actually one of the mechanisms through which they help with weight loss and blood sugar control, food moves through your stomach more slowly, you feel full sooner, and the glucose hit from a meal is blunted

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