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Through a conservative titration approach, it achieves efficacy comparable to Tirzepatide along with better safety, making it a viable option

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FGF also stimulates glial cells (Mller cells) providing trophic support to neurons

Over-the-counter products typically show moderate improvement, with combination products outperforming single-ingredient formulations

However, both can cause gastrointestinal side effects that may be additive, and dehydration from these effects could affect methotrexate clearance