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This study suggests that the introduction of such warnings could impact the decision-making of these groups

Legal basis WTO, AFAS, VJEPA, VKFTA, EVFTA, CPTPP, ACIA

doi:10.1093/ntr/ntab075 26

The group issued new policy recommendations on Monday that recommend a U.S

Nicotine pouches and gum health conclusions While unconfirmed, the data suggest that nicotine pouches may pose gum health risks for the following reasons: Nicotine can be cytotoxic (cause cell death) at higher concentrations Nicotine is capable of both pro- and anti-inflammatory effects depending on the concentration level (and under different conditions) Nicotine constricts blood vessels, which may promote and exacerbate gum disease and recession Gum recession is a known side effect of snus, which shares some similarities with nicotine pouches There are concerns that other ZYN ingredients (such as flavorings) could negatively impact oral health Although its unlikely that ZYNs are a direct cause of gum disease, those with poor gum health would be advised to proceed with caution

Reynolds for $7.8 billion