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LITERATURE REVIEW 1) Cigarette smoking effects on the respiratory epithelium The epithelium coating the upper respiratory tract acts as a first line of defense against invasive agents (pollutants, allergens, microorganisms), and it can cause upper airway symptoms and diseases when in contact with these agents.5 Inhaled cigarette smoke, both passively as well as actively, has been associated with chronic irritation and discomfort on the eyes, nose and oropharynx.6 Since 1964, when a report was published about smoking by the U.S

Vape-Specific Rules Minimum age : 21 for all tobacco and vape products (federal T-21) Online sales : Must comply with the PACT Act age verification, state tax collection, and common carrier registration Self-service : Vape products should be behind the counter or in locked displays No indoor vaping : The PA Clean Indoor Air Act prohibits vaping in most indoor workplaces and public spaces, but retail vape shops that derive a majority of revenue from vape sales may qualify for an exemption Practical takeaway : The 40% vape tax means you need to build it into your retail pricing from the start

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