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In addition, we are proposing to maintain the existing case minimums for the two measures we are proposing to modify in this rulemaking, which are a 20-episode case minimum for the IP PCI measure and a 10-episode case minimum for the Cataract Removal with IOL Implantation measure

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Use Airtight Containers Air exposure remains the primary enemy

As proposed in 428.302(c)(4), CMS would grant a reduction in the rebate amount owed if a manufacturer of an eligible drug submits to CMS a request in writing demonstrating that (1) a severe supply chain disruption has occurred during the applicable period, (2) the severe supply chain disruption directly affects the manufacturer itself, a supplier of an ingredient or packaging, a contract manufacturer, [596] or a method of shipping or distribution that the manufacturer uses in a significant capacity to make or distribute the generic Part D rebatable drug or biosimilar, and (3) the severe supply chain disruption was caused by a natural disaster or other unique or unexpected event

Because of the behavioural rewards Continued smoking is also influenced by non-nicotine effects, including the sensory-motor effects of smoking as well as smoking-associated behaviours that become reinforced

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