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But what these give us instead is an estimate of effect of smokers being assigned to use NRT, filtered through the various causal pathways of the effect of that on smoking cessation, the effect of smoking intensity on compliance and quitting without using the NRT, plus the actual effect of using NRT
Nicotine increases oxidative stress, activates NF-kappa B and GRP78, induces apoptosis and sensitizes cells to genotoxic/xenobiotic stresses by a multiple stress inducer, deoxycholate: relevance to colon carcinogenesis
Mol Reprod Dev 2021;88:141157
However, the studys limitations lie in the possible recall bias due to the cross-sectional investigation nature and social response biases due to possible reasons like social desirability bias, self-stigma, peer pressure, etc
It is formed from burning tobacco
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