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As ScienceDaily noted, "19% of the US population use at least one NSAID on a regular basis, including 30 million Americans with osteoarthritis, of whom more than 40% also have hypertension." As such, "NSAIDs, particularly ibuprofen, may be not as safe as previously thought,"Frank Ruschitzka, professor of cardiology and co-head of the Department of Cardiology at the University Heart Centre in Switzerland, told the site

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3 Diacetyl is associated with the development of the irreversible lung disease called bronchiolitis obliterans or "popcorn lung." Popcorn lung causes an irreversible loss of pulmonary function and damage to cell lining and airways