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The pivotal STEP 1 trial demonstrated that participants receiving semaglutide 2.4 mg achieved an average weight loss of 14.9% of initial body weight over 68 weeks, compared to 2.4% with placebo

Reasonable markers to track: waist circumference, weight, resting heart rate, sleep quality, and a basic liver panel (ALT, AST) before and after long cycles

For higher temperatures, use a medication cooler bag to keep the injections cool but always use a barrier between the ice (e.g

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If you have severe redness, swelling, or pain at the injection site or if you think the area is infected (warm, pus, or fever), call your doctor right away