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References to obesity, adipose tissue, mitochondrial function, or glucose-related pathways on this page are provided for laboratory research context only

Inhibition of GCH1 reduced BH4 and resulted in enhanced erastin-induced iron accumulation and lipid peroxidation, thereby enhancing ferroptosis sensitivity, while BH4 supplementation suppressed ferroptosis-related changes caused by GCH1 downregulation

16 Mohammed W, Farah S, Nassiri M, McKenna J

GmbH, Cologne, Germany (European Pat

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The effect of this study could have profound significance as it could lead to improved quality of life for the individual as well as societal improvement if academic and work-related productivity can be improved