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Research shows it can lead to small but sometimes meaningful improvements in liver enzyme levels, though results vary depending on the dose, product quality, and the group of people studied.11 56 Unlike TUDCA, which works through bile acids, milk thistle acts mainly as an antioxidant and helps limit scar tissue formation in the liver

Membership: $19.99/month after a 30-day free trial

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The company, which has ties to Marty Makary, President Donald Trumps pick to lead the FDA, also said its working with manufacturers to secure deeper discounts on the medications in late 2025 and into 2026

Common side effects include nausea, vomiting, and diarrhea, but they are generally well-tolerated and tend to improve over time

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