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doi: 10.1007/s12551-010-0041-4

Similar phenomena were found in the C@PA MN(+) and Se@PA MN groups

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Common gastrointestinal effects are the most frequently reported adverse reactions, with studies reporting variable rates of digestive symptoms: Diarrhoea and loose stools Abdominal cramping and discomfort Constipation (less common) Nausea and bloating These effects are typically dose-dependent and may improve with gradual dose escalation or taking berberine with meals